Winter 2004

 

Published by: SPESFEED (Pty) Ltd, P O Box 48, Rivonia, 2128. Tel: (011) 803-2050, Fax: (011) 803-8201

 

Inside This Issue

General News

Nucleotides: An exciting new technology

The Weaning Period

Subsidies, Maize and the Poultry Industry

A new Technology for Broiler Breeders

The Tunisian Poultry Industry

 

 

General News

 

I wrote the introductory note to this newsletter at the end of May, and by the time it was ready for posting in July, the situation had change completely. Such is the volatility of the industry that we work in. The maize price would appear to have settled at around the R 950.00 (SAFEX) mark, while the soya price, has declined following a period of farily high prices. This bodes well for animal producers. The only downside, is that many companies are long on both maize and soya.

 

Courses

Both our pig and poultry courses went off successfully during May. We have been asked to hold a feed formulation course and have planned to do so on the 4th of October. We envisage covering simple feed formulation, ingredient selection and use and some practical on farm tips. In addition, we will cover the principles of advanced techniques such as Multi-mix and Global-Mix. Please let Bianca know if you are interested in attending. We will make a decision about venue once we know just how many people are interested.

 

Format International Meeting

In March, Linda and I attended the Format International agents’ meeting on the island of Koh Sumai, Thailand. The hotel and setting exceeded all of our expectations. What is more important though, is that we were exposed to a number of exciting developments, both at Format itself and also in terms of general computing.

 

As we have come to expect, the development of Format’s software has continued at pace. For me the most significant development took the form of two new packages. The first of these being a program called Integra-Mix. Integra-mix makes use of some very advanced non-linear mathematics, developed by the University of Edinburgh, which allows for the optimisation of products manufactured over a number of different stages (phases), using common ingredients. This has enormous possibilities in the pet food industry where green and white kibbles could be used in any of five or six finished products. It also has application in the animal feed industry (which incidentally is where it all started) in that a limited number of different concentrates can be developed (formulated) in such a way that many final products could be manufactured. This has found application in companies that tailor-make dairy meals for a large number of customers. Instead of formulating and manufacturing 60 diets, it is possible to use 5 or 6 intermediate concentrates and a grain source to produce all of these diets.

 

The second major development that was released at the meeting is a package known as Quote-Master. Quote-Master adds a client file, containing a list of all of your customers, to Single-Mix. It is then possible to generate quotes, which may differ depending on discount allowed, margin or any other user-defined parameter for each client. A final report is exported to a word processor and a client-specific quote can then be printed on a company letterhead. This could then be e-mailed or posted out. This will most certainly take some of the drudgery out of price increases for many people.

 

Another major development in terms of computing (not necessarily feed formulation), is that Format have developed an ODBC (Open Database Connectivity) driver system. ODBC is a standard that allows any application to communicate with any database. Most databases, including Access, Paradox, Oracle etc., provide an ODBC interface as standard. An ODBC driver enables "calls" from an application, using SQL (Structured Query Language), to the database, and the return of data in a form understood by the application. In short, this will enable any external applications access to Format data files. This capability will provide significant benefits for both users and for Format’s future software development program.

 

Dr Michael Evans, Format’s agent in Australia has completed a "working" model for the NRC Beef (1996), which runs on Single-Mix. He has started work on a NRC Dairy model.

 

In terms of general computing, Format is making use of two exciting new products. The first is a product called Citrix. Citrix allows users to use a computer remotely over the Internet. To this end, Format now have a Citrix server in their office in St Louis in the USA, and users can log on from anywhere in the world and use the software. If you have a broadband Internet connection (ADSL), the speed at which the system operates is more than adequate. What is interesting is that you can use the software over the Internet, but use the data on your own hard drive.

 

The second system that Format has at its disposal is called WebEx. This system allows you to use (or watch) another Internet users’ computer over the web. In addition, the remote user may access your own machine, which makes remote support very easy. The true power of WebEx was demonstrated very clearly to me the other day. I participated in a WebEx training session on the Internet, hosted in Format’s office in the UK. Agents from Spain, Germany and Ireland attended. We were all linked on a conference call. In terms of what we saw and learnt, I could well have been in England.

 

Rick Kleyn

 

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Nucleotides: An exciting new technology

 

As animal production becomes more intensive, so the management of stress and it effects on the animal become more important. One of the biggest outcomes of a stressed animal is that it has a suppressed immune system. It is true that sick animals can be medicated but this should be seen as the last line of defence. We should rather avoid disease challenges through the use of rigorous bio-security (or biological risk management) programs or through the stimulation of the immune system.

 

The gastro intestinal tract (GIT) is the animal’s first line of defence against many pathogenic organisms. To fulfil its role as a part of the immune system, it is equipped with its own richly endowed immune apparatus, which exerts not only local but also systemic protective functions.

 

The epithelium of the GIT is lined with enterocytes, which are the rapidly growing cells that line the villi of the small intestine. They are involved both with the secretion of enzymes and the absorption of nutrients in addition to their function as a part of the immune system. Should the GIT be damaged in any way, as occurs at weaning in pigs or in day old chickens that become dehydrated, the villi are damaged.

 

The enterocytes, along with the other cells that make up the immune system, like bone marrow cell, macrophages and lymphocytes are characterized by their inability to produce adequate quantities of nucleotides. Nucleotides, together with adequate levels of amino acids, are the building blocks of DNA and RNA and hence the various proteins of the immune system. They are also involved in almost all activities of the cell, including catalysis, transport of energy and mediation of hormonal signals.

 

The rate of cell replication and protein accretion is dependent on the rate of DNA replication, which in turn relies on the availability of nucleotides. Thus, in order for an animal to mount a speedy immune response, which we all know to be all important, adequate amounts of specific nucleotides are essential.

 

A new product comprising a formula based on purified RNA and nucleotides called Ascogen (a product of CHEMOFORMA LTD, Switzerland) supplies those molecules required for DNA multiplication and thus rapid multiplication of immune cells and immuno-proteins.

 

According to Dr Peter Köppel of Chemoforma, Ascogen can easily be administered either via the feed or the water, with a dosage rate of 500 g/ton of feed or 250 g/1000 litre water.

 

Some multi-species research into the use of nucleotides has been published. Nucleotide addition has been shown to hasten the growth and maturation of normal enterocytes in rats and also to accelerate intestinal recovery after food deprivation or diarrhea.

 

In a paper published in Animal Science Vol. 75, Yu and his co-workers were able to demonstrate 1000 ppm of nucleotides (together with glutamine, which is a non-essential amino acid) enhanced the IgA concentration and Foot and Mouth neutralizing antibody titers. In addition, intestinal villous height and food intake was improved.

 

Table: Effect of addition of glutamine and 1000 ppm of nucleotide on weaned pigs (After Yu et al.,2002)

 

 

Control

Treatment

Daily Gain (Week 0 –8)

437

497

Average Villous Height

191b

229a

IgG mg/ml (2 hours post inoculation

29.8 b

47.9a

 

Intrestingly, reasearch in pigs has shown that the addition of nucleotides to the diet reduces the effects of Zearalenone toxicosis.  10 days after last administration of toxins no zearalenone could be detected in the liver of nucleotide-fed animals, whereas in the control, animals zearalenone was still found.  This effect was more pronounced at a higher nucleotide inclusion.

 

In the case of poultry, the effect of nucleotides on antibody production has been documented. During vaccination of poultry against Newcastle Disease Virus, the antibody titer increased more rapidly, reached higher peak values and persisted for a longer time in the treated group than in controls. In the subsequent challenge test with virulent virus, mortality decreased from 35% to 10% in the vaccinated animals that were treated with nucleotide. In these birds lymphocyte activity was markedly increased.

 

In more practical work, nucleotides were used to treat birds in a well-managed breeder farm in England. Half of the birds were fed nucleotide from 9 weeks of age. During the 14th to 15th week, an outbreak of coccidiosis was recorded, and during weeks 17 and 18 the birds were challenged with an IB variant. Believe it or not, during week 22 they were struck by an acute Marek’s infection. In the nucleotide fed group neither disease symptoms nor deleterious effects were recorded. In week 50, mortality was 17.02% in the control group, versus only 5.52% in the nucleotide treated group.

The concept of Nucleotide supplementation of diets would certainly appear to be biologically sound. The cost of the product may initially preclude it from routine inclusion in feed, but it could very realistically be used in the drinking water when birds are to be vaccinated or when they face any other form of stress.

 

Rick Kleyn

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The Weaning Period

 

The weaning period is often associated with problems such as low feed consumption and reduced growth rate. Management of the weaned pig requires special attention to housing, environment and nutrition to reduce the post-weaning growth lag and to maximise performance.

 

Environmental stressors such as weaning site, stocking density and group size can further reduce feed intake and thus the growth rate of weaned pigs. Physical gut capacity is assumed to be the primary limitation in growth in the young pig because it limits their daily feed intake and hence, daily energy intake. Due to this limitation, nutrients in the weaned pig diet are formulated as a ratio to energy. As a result, increasing the energy density of the diet subsequently increases dietary levels of other nutrients (i.e. amino acids).

 

Although increasing the energy density of weaned pig’s diets is used to improve piglet performance, the information available in the current literature on the response of the weaned pig to changes in dietary energy density, is inconclusive. To quantify the effectiveness of increasing energy density as a method to improve weaned pig performance, pigs were fed diets of different densities (Manitoba Pork - Levesque, et al 2002).

 

One experiment was completed using 252 pigs weaned at 17 days of age to an on-site or an off site nursery and provided diets of 14.0, 14.6 or 15.3 MJ DE/kg. A second experiment conducted at the PSC Elstow Research Farm using 600 pigs weaned at 19 days of age, provided diets with a DE content of 13.3, 13.9, 14.5, 15.1 or 15.7 MJ DE/kg.

 

The results of the study showed that increasing the energy density of the diet did not improve piglet performance and that the response to dietary energy was not affected by weaning site or crowding.
In both studies, feed efficiency improved as the DE content of the diet increased.
In the first experiment, the large increase in feed intake in spite of the lower feed efficiency resulted in greater daily gain for pigs on the lowest energy diet.
In the second experiment, feed intake increased slightly as the DE content decreased but no difference in pig daily gain was observed.

 

Conclusion:

 

In young pigs (10 to 25 kg BW) the limitation to growth is not due to gut capacity within the dietary digestible energy range of 14.0 to 15.3 MJ DE/kg.
Increasing energy density did not result in an improvement in pig performance in relation to daily body weight gain or protein deposition.
The study showed that growth limitations in the young pig are not overcome simply by increasing the dietary energy level. The reason for the lack of response to increasing dietary DE level is not clear but is likely to be related to fibre level and gut health.

 

Walter Scharlach

 

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Subsidies, maize and the poultry industry

 

In this month’s editorial I have taken the liberty of assembling some facts-many of which came from talks at the recent Avi-Africa Poultry Expo - and then combined these with some of my own opinions, therefor drawing some conclusions about the future.

 

Firstly, the facts: Dr Simon Shane, formerly South African but now as American as pumpkin pie, told the assembly that the average maize farmer in the US receives some $11.00 of subsidies per ton of maize produced. In addition, there is a complex mechanism to ensure that farmers will always achieve a certain ‘floor’ price. Dr Shane asserts that because all maize is traded on the Chicago bourse, these subsidies have absolutely no influence on the world price of maize. A Brazilian speaker told us just why the Brazilian poultry industry was so competitive. It is true that the Brazilian’s have cheap land and labour and that their industry is highly integrated, but the real reason for their competitive advantage is that fact that they have cheap feed inputs in the form of maize and soya. Dr Shane also made mention of this, and maintains that the South African poultry industry will never be truly competitive until such time as we have cheaper feed ingredients. A very erudite gent from the South African National Department of Agriculture, speaking from the floor, agreed with both speakers on this point.

 

Three other important sources need to be added to the above information. In a press release celebrating the centenary of SAPA, Zach Coetzee showed just how much the poultry industry has grown. More importantly, Mr Coetzee points out that the poultry industry now consumes over 3 mil tons of maize per annum and is the country’ largest consumer of maize. My own research shows that the broiler industry has grown by more than 60% in the last decade. This means that maize consumption by broilers alone will have increased by some 350 000 tons per annum during the same period. Secondly, Fred Stephens, talking at the AFMA forum in March, informed us that the USDA believes that global grain consumption is expected to exceed production for the fifth straight year. As a result, world grain stocks are at very low levels. The price of maize in the US has risen by 18% over the last two years. We need to bear in mind that as global meat consumption increases, so too, will the demand for grain. Lastly, the Landbou Weekblad (April 7), reports that Mr Bully Bothma, Grain SA chairman, is urging grain farmers to plant less maize so that the prices that producers achieve will be higher. This despite the fact that plantings were down this season as it is, and that the famous record crop of 12 mil tons is unlikely to ever be achieved again.

 

When looking at the price of the feed inputs into the South African poultry industry as compared to both the Brazilian and US industries it is important to point out that both Brazil and the US are net exporters of maize and soya beans. This means that the price that they pay for their inputs does go up and down with world markets, but by and large they are stable. South Africa finds itself in a similar position with regards soya beans as we are net importers of protein (soya beans) and also suffer from the vagaries of the world market. As an aside, there is little doubt that we will need to produce more soya in South Africa in the future. More importantly though, we are erratic producers of maize. This means that at some times our price is determined by export parity and at others it is determined by import parity. Perceptions about the rainfall, the stock carry-over and the Rand/Dollar exchange rate cause our prices to oscillate wildly between import and export parity. This makes managing grain purchasing in South Africa both difficult and risky. The irony of the situation is that South Africa is only a net importer of grain every 7 or 10 years. The good news is that when maize is priced at export parity, South African poultry farmers enjoy really competitive inputs.

 

Now to Dr Shane’s argument that subsidies have no impact on the world price: I find that I must disagree with him here. Surely if you subsidise the largest producers of maize in the world, to the tune of about 10% of the selling price (this would be far higher if you looked at the net profit of the farming venture), and you guarantee that the producer’s price will not fall below a certain unsustainable level, you are going to encourage less competitive producers to stay in business. This would not only increase the world supply, but would also depress the market price. I am not sure that this is a bad thing for South African poultry producers. As our own price is determined by the world price, surely the lower the world price of maize the better for the poultry industry in all those years where South Africa are net exporters of maize?. Sadly, this is not true for the grain producers.

 

I can’t help feeling that Mr Bothma’s urging South African farmers to plant less maize so as to move the country closer to being net importers of maize, and in so doing increase the price, may be short sighted for a number of reasons. Firstly, if we have a real ‘misoes’ and a very small maize planting, there could be serious food security issues for the whole sub-continent. Secondly, as maize is the staple diet of much of our population a consistently high price would put severe pressure on the poor and would have a negative effect on inflation. Lastly, higher maize prices are ultimately going to make the maize industries biggest customer (the poultry industry) less competitive globally: and instead of growing as we are now, we could well see the industry shrink.

 

On a more positive note, South Africa is situated just south of the legendary "bread basket" of Africa. Things may have gone awry in Zimbabwe for the moment, but the grain and soya production in Zambia is increasing in a most encouraging manner. Although the infrastructure in terms of storage is not all that well developed in these countries, there are South African companies who have seen the possible advantages of producing grain in the north and storing it in the south where it will be used. There is nothing like a reliable market to stimulate production, so let’s hope that the supply of ingredients from our neighbouring countries becomes a reality. Remarkably, Mr Bully Bothma believes that South African maize farmers will be able to meet the World Food Programme’s (WFP) demand for extra food aid to deal with the Southern African food crisis. (Farmers Weekly, April 30).

 

How, then, do we as a country move forward? We find ourselves in the unenviable situation of being part of the global village where the free market reigns supreme. South Africa, along with many other smaller economies, does not enjoy any form of agricultural subsidies but the same can not be said about the Europeans and Americans. I am not suggesting that the state tampers with the price of maize in any way or implements any form of subsidy. However, the only way that we will continue to have cheap food for our people (both the staple food that they eat and poultry meat) is if grain production is promoted in some way. Perhaps some form of floor price mechanism could be implemented so that if the maize price falls below the production cost, the grain farmers would not run the risk of insolvency. This would be of great comfort to both emerging farmers and those farmers who farm in less than ideal conditions. We need to bear in mind that South Africa does not have the climate or soils that either the Brazilians or the US enjoy so our farmers are already at a disadvantage.

 

As the poultry industry-and so local consumption- grows, South Africa will move further away from being net exporters to becoming net importers of grain. Our average grain price will move closer to the import parity price and the poultry industry will find it more difficult to compete globally. With demand for grain increasing, world grain prices are unlikely to drop in real terms, which could further exacerbate our situation. The only consolation is that if the world price rises, so too do the input costs of all of the global players in the poultry industry.

 

The poorer members of our society are likely to become poorer and the government will struggle to keep food inflation under control. As an industry, we may well be forced to look North, both for a supply of ingredients or even as a centre for production. Let us hope for some form of state initiative to stimulate, rather than reduce, grain production in this country.

 

Rick Kleyn

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A new Technology for Broiler Breeders

 

Because the broiler industry is rapidly expanding and because selection for greater body weight in broilers has been at the expense of egg lay, the production of more eggs is becoming increasingly important. For example, to meet global demands at current expansion rates, an extra 15 million broiler breeders will be needed annually to produce 1.5 billion more broilers for human consumption. To address this need, LSU AgCenter researchers have demonstrated the feasibility of increasing egg production in broiler breeder hens using chicken inhibin-based immunopharmaceuticals.

 

Inhibin is a peptide hormone produced in the ovary that acts as a brake on egg production. When an inhibin antigen is presented to the bird in the context of a foreign protein, the animal’s immune system is fooled into attacking inhibin. Similar to autoimmune diseases (for example, multiple sclerosis), the bird raises antibodies to - and thereby inactivates - endogenous inhibin, which in essence releases the brake on egg production. We have shown that immunoneutralization of inhibin by vaccination increases ovulation rates in quail, chickens (both egg- and meat-type) and turkeys.

 

Over the past nine years, LSU AgCenter scientists have been working in close co-operation with multiple corporate sponsors to develop safe, inexpensive and effective inhibin vaccines. The scientific development of these patented vaccines (chicken inhibin-based antigens) has led to the recent discovery of a more practical synthetic vaccine. The vaccine is comprised of a Multiple Antigenic Peptide (MAP) with a poly-lysine backbone linked to four peptides comprising the first 26 amino acids of chicken alpha-inhibin. When appropriately administered to breeder hens, it appears to be on track to produce an increase of around 10 percent in hen-day egg production during the industry standard 40 weeks of lay. This means that producers who use the vaccine could experience an increase in egg lay of about two dozen eggs per housed hen. This represents the single largest on-the-spot enhancement of reproductive performance in the history of the poultry industry. Indeed, it has taken the breeders of egg-type chickens about 20 years to achieve a lesser (about 7 percent) increase in egg lay by traditional methods.

 

Depending on management, the vaccine increases the onset, magnitude and duration of egg lay. Of equal importance, regardless of how the laying curve is affected, inhibin immunoneutralization has shown no untoward effects on eggs produced by vaccinated hens or on the chicks that hatch from these eggs. The intervention does not alter hen body weight and livability, egg size and egg shell thickness, the fertility and hatchability of eggs or livability of hatchlings to harvest age.

 

This remarkable story does not end with the hen. Active immunization against inhibin holds significant promise in enhancing the fertilizing capacity of roosters as well. In a preliminary study, this new vaccine was found to accelerate puberty and increase fertility in aged males.

 

With the continued emphasis on selection for body weight in yield-type broiler breeders, overall egg fertility is declining at an alarming rate (about a half percent annually). This is most likely due to decreased gonadal function and copulation efficiency of large-bodied males. Marked declines in fertility are now commonly seen in flocks with aged males (more than 36 weeks old). This has caused producers to "spike" their old flocks with young males to increase fertility. This practice is expensive because additional flocks of males have to be maintained and risky from a bio-security standpoint because the standard "all-in, all-out" practice used in poultry is violated when young outsider males are introduced into established flocks.

 

Inhibin immunoneutralization of broiler breeders is a revolutionary approach that holds promise to change the poultry industry forever in a similar manner as bovine soma-totropin (BST) changed the dairy industry.

 

Daniel G. Satterlee

Department of Animal Sciences, LSU AgCenter, Baton Rouge, La.

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The Tunisian Poultry Industry

 

During June I was fortunate enough to spend a week in Tunisia. I was invited by the American Soybean Association (ASA) to form part of the team that presented a "Cours sur la Formulation des Aliments" at the Ecole Nationale de Médicine Vétérinaire in Tunis. The three-day course included a visit to a broiler farm. I was also able to spend a day with the nutritionists at Provital, a leading manufacturer of animal feed in Tunisia and a day with the staff of the Groupment Interprofessionnel des Produits Avicoles (GIPA), which is the body that controls the poultry industry in Tunisia.

 

Tunisia has a population of around 10 million, and apart from being the third largest producer of olives in the world, they also produce a wide range of agricultural products, including some excellent local wines. The country is said to be the most "European" of those countries in North-Africa but has maintained it’s essential African feel, which makes South Africans feel very at home there. The economy is doing well as is evidenced by the large number of new buildings and building sites that one sees. From a poultry perspective, the country has a small but vibrant poultry industry, and although Tunisia is Africa’s Northern most country, the structure of its poultry industry should be of interest to all African poultry producers.

 

Although the last day of my Tunisian trip was spent at the offices of GIPA, as arranged by Dr. Riadh Karma, it is here that I got a broad overview of the poultry industry in the country, so I will begin with this. Firstly, the most striking aspect of the Tunisian poultry industry is that production control is exercised via the offices of GIPA. This is achieved by a very simple method. Bird numbers are controlled by regulating the number of breeding birds that each of the 36 hatcheries in the country are allowed to keep. Hatcheries are rewarded for good production results and good record keeping. They are penalised for violating norms such as keeping flocks in lay for too long. All day old chicks have to be sold to producers that are registered members of GIPA. GIPA is essentially controlled by the Ministry of Agriculture and is funded through member subscriptions and a levy on imported feed ingredients.

 

The influx of some 5 mil tourists a year into Tunisia during the summer, coupled with religious festivities such as Eid-ul Adha and Ramadaan give rise to well established cyclical demand patterns. During times of surplus GIPA builds up stocks of broilers and eggs, which are later sold. In addition, they import hatching eggs during times of peak demand. The system would appear to be most effective, as the figures that I was shown would suggest that Tunisian poultry farmers are guaranteed a fair return at almost all times of the year. The profitability of the industry is also monitored by GIPA and to this end they do a complete audit of some 15 to 20 flocks per year.

 

Tunisian’s consume some 138 eggs per capita per annum, and some 260 farmers control the 5.3 million laying hens, most of whom mix their own feed. Surprisingly, most of the eggs produced are white. The story goes that during a Salmonella outbreak some years ago, white eggs were marketed as ‘clean’ and the practice and perception has continued. Sadly, I did not visit a layer operation. The egg industry is essentially static in line with the country’s population growth.

 

Broiler consumption is around 12 kg/capita per annum, with Turkey consumption at around the 3.5-kg mark. There are some 4000 broiler producer's in Tunisia, most of who buy feed from the small but dynamic feed industry. The farm that I visited, was in Boumell, just South of Tunis, and belonged to Mr Ben Slimane. It was the oldest farm in the group controlled by his family. Despite this, the old houses all had new nipple drinkers and feeder pans installed. Tunnel ventilation and wet walls were in the process of being fitted to all of the houses. The birds being produced were ISA broilers, which are an unfamiliar strain to me. The Tunisian industry no longer uses anti-biotic growth promoters in line with their European neighbours. The stocking densities used are in the 12 to 14 bird/m2 range. As with South Africa, the market demands a 1.2 kg dressed bird, so most birds are processed at around 40 days of age. The broiler industry is growing at about 9% per annum.

 

From a feed perspective, nearly all of the ingredients used in the feed industry are imported, most in the form of maize and soybean meal. My personal exposure comprised a visit to the feed company Provital in Grombalia. I was impressed by their old but well maintained mill, their excellent laboratory and their staff. They showed me plans of a proposed new mill. I was able to not only learn more about the Tunisian feed industry, but was also able to have a look at their formulations. In broad terms their formulations are sound, and meet the market requirements, but the energy levels used are low compared to what I am used to. On the other hand, the layer diets contained protein levels of as high as 17%, which I felt was not entirely necessary.

Rick Kleyn

 

SPESFEED (Pty) Ltd.

Animal Nutrition Consultants

SPESFEED NEWS is published by the consultants at SPESFEED (Pty) Ltd. The purpose of the newsletter is two fold. It serves both as a source of information for those involved in animal agriculture as well as a means for us to maintain contact with our clients.

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